hoxu released the first version of his handbook for Supybot, named Supybook, a few days ago. It contains many good tips and instructions for setting up, running and maintaining a Supybot. It already covers a great deal of things one would consider sooner or later when running a Supybot. I hope it will be well received by the Supybot developers and community, it deserves it. (I have even contributed with a few small things. 🙂 )
Have a look at it if you are using, running, or planning to use a Supybot.
Update 2011-10-07: Supybook has changed hosting .